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InChi: InChI=1S/C20H20ClF2N3O3S/c21-15-11-17(23)19(30(28
there is no major decrease in mitochondrial import receptor subunit TOM20 homolog (TOMM20) or in the cytoskeleton protein β-actin
Displays some inhibitory activity towards c-Kit
JTK-853 induces apparent Huh-7
G5-7 tanediol InChi: InChI=1S/C20H20ClF2N3O3S/c21-15-11-17(23)19(30(28G5 7, an orally active and allosteric JAK2 inhibitor, selectively inhibits JAK2 mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3 by binding to JAK2. G5 7 induces cell cycle arrest, apoptosis and possesses antiangiogenic effect. G5 7 has the potential for glioma study. Product information CAS Number: 939681 36 4 Molecular Weight: 411. 44 Formula: C24H23F2NO3 Chemical Name: tert butyl (3Z,5Z) 3,5 bis[(2 fluorophenyl)methylidene] 4